
Semaglutide Single vial · Incretin / GLP-1
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For laboratory research use only. Not for human or veterinary use.
Buying at volume? Semaglutide factory direct
About Semaglutide+
About Semaglutide
Semaglutide (development code NN9535; licensed medicines) is a synthetic analogue of glucagon-like peptide-1 (GLP-1), a hormone the gut releases after eating. Novo Nordisk developed it after liraglutide: it differs from human GLP-1 at two positions and carries a fatty acid chain, changes designed to resist breakdown and to bind albumin in the blood, so it lasts much longer than natural GLP-1 (Lau et al., J Med Chem 2015). It is licensed in the UK, EU and US as a medicine for type 2 diabetes and for weight management alongside diet and exercise. These licences rest on large randomised trials, including the SUSTAIN trials in type 2 diabetes and the STEP trials in obesity. In the US is also licensed for some adults with heart disease and overweight or obesity, based on the SELECT trial in 17,604 people (Lincoff et al., NEJM 2023). Most of what is known about how it acts on appetite circuits in the brain comes from rat and mouse studies (Gabery et al., 2020). The research material supplied here is not the licensed medicine. Supplied for laboratory research use only.
Mechanism
Semaglutide binds and activates the GLP-1 receptor, a G-protein coupled receptor found on the insulin-making beta cells of the pancreas and in the gut and brain. In the pancreas this increases insulin release when blood glucose is high and lowers glucagon release, and GLP-1 receptor signalling also slows stomach emptying. In rats and mice, semaglutide did not cross the blood-brain barrier but reached brain areas next to it, such as the area postrema, and activated nerve cells in several regions linked to food intake (Gabery et al., 2020).
Research on Semaglutide
Storage and handling
- Reconstituted 2 to 8 C up to 56 days.
- Once reconstituted, keep refrigerated and avoid repeated freeze and thaw cycles.
- Bacteriostatic water is the usual diluent. The volume added sets the concentration in mg per mL.
- Vials carry a batch number for your laboratory records. Recent independent lab results are published in our COA Library.
FAQs
Can I order a single vial of Semaglutide without a minimum order?+
Yes. The single-vial range exists precisely so a laboratory can take one vial of Semaglutide rather than a full Factory Direct kit of 10. There is no minimum order quantity on this format.
How quickly does a Semaglutide single vial ship in the UK?+
Single vials are held in our UK facility and dispatched within 24 hours of a cleared payment on working days, on a tracked UK service. Orders placed at the weekend go out on the next working day.
How does the single vial differ from the factory-direct box?+
The compound and the manufacturing source are the same. The Factory Direct kit is a 10-vial pack and a lower per-vial cost, while the single vial is one vial from UK stock for small-scale or pilot work.
What purity is stated for Semaglutide?+
99%+ manufacturer-stated purity. Buyers are encouraged to run independent third-party verification, and our testing directory lists laboratories that perform it.
Is this Semaglutide vial for human use?+
No. Every Peptx product, including the single-vial range, is supplied strictly for laboratory research. It is not for human consumption, diagnosis, treatment or any clinical use.
What is Semaglutide?+
Semaglutide is a long-acting synthetic analogue of the gut hormone GLP-1, developed by Novo Nordisk. It is the active substance in the licensed medicines. The material supplied here is not the licensed medicine and is for laboratory research use only.
How does Semaglutide work?+
It activates the GLP-1 receptor, which increases insulin release when blood glucose is high, lowers glucagon release and slows stomach emptying. In rats and mice it also acted on appetite-related brain areas that sit just outside the blood-brain barrier.
Has Semaglutide been tested in people?+
Yes. Large randomised trials, including the SUSTAIN trials in type 2 diabetes, the STEP trials in obesity and the SELECT cardiovascular outcomes trial, underpin its licences in the UK, EU and US. Our research overview covers the details.
How is Semaglutide stored?+
Store the freeze-dried powder sealed, cold and away from light, following standard laboratory peptide storage procedures. See the product specifications for detailed storage requirements.
Other single vials in Incretin / GLP-1
Strictly for laboratory research. Not for human consumption, diagnosis or treatment.

