Tirzepatide is a synthetic dual GIP and GLP-1 receptor agonist referenced in published incretin pharmacology research. Published preclinical and clinical work has characterised effects of simultaneous engagement of both incretin receptors. Supplied as a research reference material only, not for human consumption.
Dispatch
48h factory
Form
Lyophilized
MOQ
10 vials
Suppliers
Multi-source
What is Tirzepatide (LY3298176)?
Tirzepatide, marketed as Mounjaro and Zepbound as a licensed prescription medicine, is a synthetic peptide that acts as a dual agonist at both the GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide) receptors. The licensed medicine is a prescription-only product regulated by the MHRA; the material referenced here is unlicensed research reference material and is not a medicine.
The compound is based on the native GIP sequence with substitutions that confer GLP-1 receptor agonist activity, producing a single molecule that engages both incretin pathways. A C-20 fatty diacid moiety extends its plasma half-life to approximately 5 days.
Tirzepatide has been the subject of the SURPASS and SURMOUNT clinical trial programmes and is referenced widely in the published incretin literature.
Dual Receptor Mechanism (Published Research)
Published research has characterised tirzepatide as engaging two distinct incretin receptor pathways simultaneously.
GIP Receptor
Published in-vitro and clinical pharmacology has characterised GIP receptor activation in glucose-dependent insulin secretion and adipose tissue signalling pathways.
GLP-1 Receptor
GLP-1 receptor activation referenced in published research alongside insulin secretion, glucagon suppression and gastric emptying endpoints.
Combined GIP/GLP-1 Engagement
Published preclinical and clinical data has reported combined-pathway effects in animal and trial populations. Reported effects describe trial endpoints, not predictions about any individual.
Research Applications
- Incretin pathway research: Investigated in published research on simultaneous engagement of GIP and GLP-1 receptors in glucose and lipid metabolism models.
- Adipose tissue research: Referenced in published in-vitro and animal literature on GIP receptor signalling in adipocyte function and white adipose tissue biology.
- Beta-cell research: Referenced in literature on dual incretin agonism in pancreatic beta-cell signalling and insulin secretory capacity.
- Comparative pharmacology: Used as a published reference compound alongside semaglutide (single GLP-1) and retatrutide (triple GIP/GLP-1/glucagon).
- Peptide engineering: Referenced in literature on how GIP-based sequence modifications confer activity at the GLP-1 receptor in bispecific peptide design.
Storage, Handling, and Reconstitution
Long-Term Storage
Store unreconstituted lyophilized Tirzepatide at -20°C to -80°C for optimal stability (24+ months).
Short-Term Storage
Unreconstituted vials may be stored at 2-8°C for up to 90 days during active research use.
Reconstitution
Reconstitute with bacteriostatic water. Add solvent slowly along the vial wall and gently swirl until dissolved. Do not vortex.
Post-Reconstitution
Store at 2-8°C and use within 28 days. Aliquot into single-use portions for long-term frozen storage.
For laboratory handling and storage information, see our research equipment overview.
Quality Assurance
Peptx sources all Tirzepatide exclusively from vetted manufacturers, gauged on independent testing at accredited ISO 17025 labs plus active community feedback, all maintaining rigorous internal quality control.
Multi-source vetted suppliers
Suppliers are vetted across multiple signals: independent ISO 17025 lab testing and live community feedback.
48 Hour Dispatch
Orders dispatched within 48 hours from the factory with full tracking.
Frequently Asked Questions About Tirzepatide
What is Tirzepatide used for in research?▼
How does Tirzepatide differ from Semaglutide?▼
What purity is Peptx Tirzepatide?▼
What doses of Tirzepatide are available?▼
Can I buy Tirzepatide for research in Europe?▼
Related Research Peptides
Semaglutide
Single-acting GLP-1 receptor agonist for comparative metabolic research.
GLP-1/GIP/GCGR TripleRetatrutide
Triple agonist peptide adding glucagon receptor activation to incretin pathways.
Copper PeptideGHK-Cu
Copper peptide complex for tissue remodelling and cellular senescence research.
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Tirzepatide is sold by Peptx strictly for laboratory and research purposes only. It is not intended for human consumption, veterinary use, food additive, or cosmetic applications. By purchasing this product, the buyer confirms it will be used exclusively for qualified scientific research.