Question 1

What is CJC-1295 with DAC?

Accepted Answer

CJC-1295 with DAC is a synthetic analogue of the first 29 amino acids of growth hormone-releasing hormone (GHRH), with four amino-acid changes and an added albumin-binding linker called a drug affinity complex (DAC). The linker lets it attach to albumin in the blood, so it stays in circulation far longer than natural GHRH. It is supplied here for laboratory research use only.

Question 2

How does CJC-1295 with DAC work?

Accepted Answer

It binds the GHRH receptor on growth-hormone-producing cells in the pituitary gland, which triggers growth hormone (GH) release, and GH in turn raises IGF-1. Because it is bound to albumin, the signal lasts for days. In healthy volunteers, GH still rose and fell in pulses, but the level between pulses was higher.

Question 3

Has CJC-1295 with DAC been tested in people?

Accepted Answer

Yes, in a small number of short studies in healthy adults. Two randomised, placebo-controlled trials found dose-related rises in GH and IGF-1 lasting from about six to eleven days after a single dose, with no serious adverse reactions reported (Teichman et al., 2006). There are no published trials of clinical outcomes or long-term safety.

Question 4

How is CJC-1295 with DAC stored?

Accepted Answer

Store the freeze-dried powder sealed, cold and away from light, following standard laboratory peptide storage procedures. See the product specifications for detailed storage requirements.

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