CJC-1295 Without DAC

CJC-1295 without DAC, also sold as Modified GRF 1-29 (Mod GRF 1-29), is a synthetic 29-amino-acid analogue of growth hormone-releasing hormone (GHRH). It is the first 29 amino acids of human GHRH with four amino-acid substitutions that make it more resistant to breakdown by enzymes. It lacks the extra lysine and albumin-binding linker (the "drug affinity complex") that keep CJC-1295 with DAC in the blood for days. In the developer's published work the name CJC-1295 was given to the DAC compound (Jetté et al., Endocrinology 2005), so the human studies of "CJC-1295" describe the DAC version, not this one. A 29-amino-acid peptide sold under the CJC-1295 name was identified by a doping-control laboratory in an unlabelled preparation (Henninge et al., Drug Test Anal 2010). There appear to be no published controlled human studies of this compound. A 2026 review described it as essentially uncharacterised in peer-reviewed human research, with no human half-life reported, and noted that claims about it are extrapolated from related peptides such as sermorelin (Dominikowski et al., Front Endocrinol 2026). Results from the DAC version cannot be assumed to apply, because that version binds albumin. Its effects and safety in people are unknown. Supplied for laboratory research use only.